Assessing Predictive Ability of Biomarkers for Pediatric Acute Kidney Injury: Methodological Issues
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چکیده
منابع مشابه
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متن کاملBiomarkers for Acute Kidney Injury
Acute kidney injury (AKI) has been recognised as a major public health problem. It affects >50% of patients in the Intensive Care Unit (ICU) and is associated with serious shortand long-term complications, premature death and high financial healthcare costs (Mehta et al. 2015; Hoste et al. 2015; Lewington et al. 2013). The consensus definition of AKI has emerged from the Risk, Injury, Failure, ...
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Acute kidney injury (AKI) represents a common and devastating problem in clinical medicine. A major reason is the lack of early biomarkers for AKI, and hence an unacceptable delay in initiating therapy. Fortunately, the application of innovative technologies has uncovered several novel biomarkers. The most promising of these are included in a putative AKI biomarker panel, consisting of neutroph...
متن کاملBiomarkers of acute kidney injury.
Creatinine remains the standard for laboratory diagnosis of AKI. Efforts to prevent nephrotoxicity have been harmed by the delay in the diagnosis of AKI criteria by using only the creatinine as a marker, therefore there is great interest in identifying early reliable biomarkers. Moreover, early treatment of ARF can be correlated with a better prognosis and identification of biomarkers for early...
متن کاملBiomarkers of Acute Kidney Injury
The diagnosis of acute kidney injury (AKI) is usually based on measurements of blood urea nitrogen (BUN) and serum creatinine. BUN and serum creatinine are not very sensitive or specific for the diagnosis of AKI because they are affected by many renal and nonrenal factors that are independent of kidney injury or kidney function. Biomarkers of AKI that are made predominantly by the injured kidne...
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ژورنال
عنوان ژورنال: The Annals of Thoracic Surgery
سال: 2018
ISSN: 0003-4975
DOI: 10.1016/j.athoracsur.2018.01.044